Publications

Global metabolomic profiling of tumor tissue and paired serum samples to identify biomarkers for response to neoadjuvant FOLFIRINOX treatment of human pancreatic cancer

Authors: Amrutkar M, Guttorm SJT, Finstadsveen AV, Labori KJ, Eide L, Rootwelt H, Elgstøen KBP, Gladhaug IP, Verbeke CS
Journal: Molecular Oncology
Year: 15 November 2024

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Unravelling the complexities of resistance mechanism in pancreatic cancer: Insights from in vitro and ex-vivo model systems

Authors: Lencioni G, Gregori A, Toledo B, Rebelo R, Immordino B, Amrutkar M, Xavier CPR, Kocijančič A, Pandey DP, Perán M, Castaño JP, Walsh N, Giovannetti E
Journal: Semin Cancer Biol, 106-107, 217-233 (in press)
Year: 17 September 2024

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Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas

Authors: Brekke RS, Gravdal A, El Jellas K, Curry GE, Lin J, Wilhelm SJ, Steine SJ, Mas E, Johansson S, Lowe ME, Johansson BB, Xia X, Fjeld K, Molven A
Journal: Human Molecular Genetics
Year: 1 June 2024

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Preoperative profiles of plasma amino acids and derivatives distinguish periampullary cancer and benign disease

Authors: Stina Margrethe Stålberg, Laxmi Silwal-Pandit, Nasser Ezzatkhah Bastani, Daniel Johan Hammer Nebdal, Ole Christian Lingjærde, Bjørn Steen Skålhegg & Elin Hegland Kure
Journal: BMC Cancer
Year: 03 May 2024

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Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol flux in pancreatic cancer cells

Authors: Li Y, Amrutkar M, Finstadsveen AF, Dalen KT, Verbeke CS, Gladhaug IP
Journal: Cancer Cell International
Year: 2023;23:276

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Comprehensive ctDNA measurements improve prediction of clinical outcomes and enable dynamic tracking of disease progression in advanced pancreatic cancer

Authors: Lapin M, Edland KH, Tjensvoll K, Oltedal S, Austdal M, Garresori H, Rozenholc Y, Gilje B, Nordgård O
Journal: Clinical Cancer Research
Year: 2023 (online ahead of print)

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Neoadjuvant chemotherapy is associated with an altered metabolic profile and increased cancer stemness in patients with pancreatic ductal adenocarcinoma

Authors: Amrutkar M, Verbeke CS, Finstadsveen AV, Dorg L, Labori KJ, Gladhaug IP
Journal: Molecular Oncology
Year: 2023;17:59-81

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Pancreatic stellate cell-induced gemcitabine resistance in pancreatic cancer is associated with LDHA- and MCT4-mediated enhanced glycolysis

Authors: Amrutkar M, Berg K, Balto A, Skilbrei MG, Finstadsveen AV, Aasrum M, Gladhaug IP, Verbeke CS
Journal: Cancer Cell International
Year: 2023;23: 9

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Proteome analysis of pancreatic tumors implicates extracellular matrix in patient outcome

Authors: Silwal-Pandit L, Stålberg SM, Johansson HJ, Mermelekas G, Lothe IMB, Skrede ML, Dalsgaard AM, Nebdal D, Helland Å, Lingjærde OC, Labori KJ, Skålhegg BS, Janne Lehtiö, Kure EH
Journal: Cancer Research Communications
Year: 2022;2:434-446

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The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice

Authors: Fjeld K, Gravdal A, Brekke RS, Alam J, Wilhelm SJ, El Jellas K, Pettersen HN, Lin J, Solheim MH, Steine SJ, Johansson BB, Njølstad PR, Verbeke CS, Xiao X, Lowe ME, Molven A
Journal: Pancreatology
Year: 2022;22: 1099-1111

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C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer

Authors: Liu X-Z, Ruling A, Choi MH, Pedersen L, Lepland J, Takle ST, Madeleine N, Peters SD, Wogsland CE, Grøndal SM, Lorens JB, Goodarzi H, Lønning PE, Knappskog S, Molven A, Halberg N
Journal: Nature Communications
Year: 2022;13: 69

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Prognostic value of disseminated tumor cells in unresectable PDAC: a prospective observational study

Authors: Nordgård O, Lapin M, Tjensvoll K, Oltedal S, Edland KH, Neverdahl NB, Fastens D, Garresori H, Glenn N, Smaaland R, Gilje B
Journal: BMC Cancer
Year: 2022;22:609

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Prognostic impact of resection margin status on distal pancreatectomy for ductal adenocarcinoma

Authors: Blomhoff Holm M, Verbeke CS
Journal: Current Oncology
Year: 2022;29:6551-6563

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Tumour size and T-stage in pancreatic cancer resection specimens depend on the pathology examination approach

Authors: Tran ML, Blomhoff Holm M, Verbeke CS
Journal: Cancers
Year: 2022;14:2471

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Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing.

Authors: Tjensvoll K, Lapin M, Gilje B, Garresori H, Oltedal S, Forthun RB, Molven A, Rozenholc Y, Nordgård O.
Journal: Sci Rep.
Year: 2022 Apr 6;12(1):5816

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KRAS mutation analysis by droplet digital PCR of duodenal juice from patients with MODY8 and other pancreatic diseases.

Authors: Choi MH, Tjora E, Forthun RB, Engjom T, Ræder H, Hovland R, Molven A.
Journal: Pancreatology
Year: 2021 Dec;21(8):1460-1465

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Morphological heterogeneity in pancreatic cancer reflects structural and functional divergence

Authors: Santha P, Lenggenhager D, Finstadsveen A, Dorg L, Tøndel K, Amrutkar M, Gladhaug IP, Verbeke C
Journal: Cancers
Year: 2021;12:895

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Kreftforeningens nasjonale ekspertgruppe på pancreaskreft

Authors: Gladhaug IP, Grindedal E, Kaasa S, Kure E, Labori KJ, Molven A, Nordgård O, Rødland AM, Tasken K, Verbeke C
Journal: OnkoNytt
Year: 2021;1:74-77

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Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model

Authors: Schulz CW, Ruiz de Garibay G, Langer A, Liu J-B, Dhir T, Leitch C, Wessner CE, Mayoral M, Zhang B, Popa M, Huang C, Kotopoulis S, Luo X, Zhen Y, Niu S, Torkzaban M, Wallace K, Eisenbrey JR, Brody JR, McCormack E, Forsberg F
Journal: Cancer Biology & Therapy
Year: 2021;22:204-215

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